Most of the left ventricular high voltage is caused by left ventricular hypertrophy, it should be treated for the original disease, and can take ACEI class, ARB class, β-blocker or ARNI. 1. ACEI: Angiotensin converting enzyme inhibitors, such as enalapril, captopril, etc. This kind of drugs by blocking the angiotensin converting enzyme, thus antagonizing the renin-angiotensin-aldosterone system, so as to reduce the blood pressure, and also to improve the function of ventricular remodeling. 2. ARB class: angiotensin II receptor antagonists, such as valsartan, irbesartan, etc., this kind of drugs through the blockade of angiotensin II receptor, thereby antagonizing the renin-angiotensin-aldosterone system, resulting in lowering blood pressure, and also improve ventricular remodeling function. 3. β-blocking drugs: by blocking β receptors, thereby slowing down the heart rate, reducing myocardial oxygen consumption, producing antihypertensive effect, and also improve the function of ventricular function. 4. ARNI: angiotensin receptor enkephalinase inhibitor, the drug name is sakubutra valsartan sodium, is a new type of anti-heart failure drugs, lowering blood pressure at the same time can improve cardiac function. 5. There are also diuretics such as hydrochlorothiazide, spironolactone, etc.; calcium channel blockers such as isobarbital and diltiazem. Each drug has corresponding contraindications, must be used reasonably under the guidance of the doctor.