Hands soaked in water rot, consider the hands in the water caused by immersion in the skin folds, can be adjusted through general treatment, medication and other measures. Hands soaked in water for a long time, the stratum corneum absorbs water and expands, but the dermis does not absorb water, so it causes local wrinkles. 1. General treatment: first of all, avoid soaking in the water again, dry your hands in time, keep your skin clean, moisturized and dry. 2. You can use local topical prickly heat powder, glycerite lotion and other drugs to assist in the treatment; if the skin’s erosion occurs, you can use boric acid solution wet compresses; if there are signs of redness and swelling and infection, topical erythromycin ointment, fusidic acid cream and other antibiotic drugs. The hand soaked in water rotten, if not self-recovery, need to use drugs under the guidance of a doctor.