Bile duct stones in the right lobe of the liver are intrahepatic bile duct stones, whereas they are more commonly found in the right posterior lobe of the liver due to the anatomical relationship between the hepatic duct and the confluence of the common hepatic duct, which can easily lead to poor bile drainage. The current causes of intrahepatic bile duct stones are mainly related to biliary tract infections, biliary parasites, biliary stasis, as well as bile duct metaplasia and malnutrition, and most of the stones are brown bile pigment stones containing bacteria. Long-term presence of bile duct stones in the right lobe of the liver may lead to bile duct obstruction, causing bile duct narrowing at the lesion and bile duct dilatation proximal to the obstruction; it may also cause recurrent biliary duct infections and even liver abscess, biliary hemorrhage, biliary cirrhosis and portal hypertension, and in some patients, cholangiocarcinoma. Therefore, for symptomatic bile duct stones in the right lobe of the liver, active treatment is needed, and different treatment methods are chosen according to the number, size and specific location of the stones.