Creatinine 180μmol/L is not a stage of renal failure.
Staging according to the patient’s blood creatinine level: renal function compensation stage: 133~177 μmol/L; renal function failure stage: 186~442 μmol/L; renal failure stage: 451~707 μmol/L; uremia stage: ≥707 μmol/L. Creatinine 180 μmol/L is close to renal function failure stage and has not reached renal failure stage.
Creatinine is the metabolic end product of creatine in muscle tissue. Creatinine does not bind with protein in the blood and can freely pass through the glomerulus, which is the most commonly used indicator to indirectly reflect the glomerular filtration function. When glomerular filtration is impaired, the body’s serum creatinine may be elevated, suggesting the presence of renal insufficiency.
Elevated creatinine is common in acute kidney injury or chronic renal insufficiency. If acute kidney injury occurs, we need to clarify whether it is caused by pre-renal factors (such as effective blood volume insufficiency), renal factors or post-renal factors (such as urinary tract obstruction, etc.), and actively treat the cause, and the patient’s blood creatinine may be restored to normal level.
If the creatinine is elevated due to chronic renal insufficiency, the treatment is mainly to lower blood pressure, reduce urinary protein, and delay the progressive deterioration of renal function. The more commonly used drugs are nifedipine extended-release tablets, fosinopril, valsartan, etc. If the patient’s pathologic type is dominated by active lesions, immunosuppressants such as prednisone acetate, cyclosporine, cyclophosphamide, etc. may also be applied.
All of the above medications should be used under the guidance of a doctor, avoiding self-medication. If the patient found that the blood creatinine is elevated, it is recommended to go to the regular hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.