Cardia cancer can be metastasized to multiple tissues and organs such as liver and lungs through blood line. Cardia cancer belongs to one of the common types of gastric cancer, which is a malignant tumor disease with multiple metastatic pathways, such as hematogenous metastasis, lymphatic metastasis and so on. In patients with hematogenous metastasis, tumor cells can be transferred to multiple tissues and organs through blood flow, such as liver, lung, bone, intracranial and skin tissues, etc. In patients with advanced stage, pancreatic cancer can be transferred to multiple tissues and organs through blood flow. In advanced stage patients, hematogenous metastasis can account for more than 60%, and the first to metastasize is the liver, followed by the lungs, peritoneum, adrenal glands and so on. And lymphatic metastasis also belongs to the important ways of cardia cancer metastasis, including gastric wall lymph nodes, left supraclavicular lymph node metastasis and so on. Once pancreatic cancer patients are diagnosed, they should carry out active and effective treatments, such as surgery, radiotherapy and chemotherapy under the guidance of physicians in a timely manner. It is necessary to keep optimistic and positive attitude, which is beneficial to the prognosis of the disease.