A headache in half of the face may be trigeminal neuralgia. Trigeminal neuralgia is a primary neuralgia, the exact cause of which is not clear. It may be related to the compression of the trigeminal nerve in the cerebral bridge by anomalous twisted blood vessels or local demyelinating changes, and is mainly treated clinically with carbamazepine and oxcarbazepine. Patients with trigeminal neuralgia present with sudden onset of severe pain, usually limited to the area of distribution of the sensory branches of the trigeminal nerve, most patients present with one side of the face, with a short duration, either 1-2 minutes or a few seconds, the pain can stop suddenly, and intermittent patients are normal. Patients can have several attacks a day or even dozens of attacks. Patients may experience reflex twitching of the facial muscles, also known clinically as painful twitching.