Recently, many people are complaining about the vagaries of the weather, and some people in the WeChat “circle of friends” jokingly say that in just 48 hours they have spent four seasons: spring, summer, autumn and winter. The sudden rise and fall in temperature can cause various vascular system diseases. Among them, some diseases have similar symptoms, which can cause problems in determining the disease, such as chest pain. When aortic coarctation, which is prone to sudden death, strikes, one of the most obvious symptoms is chest pain, but chest pain is not always caused by coarctation, and similar chest pain symptoms can occur in myocardial infarction. In this regard, Professor Jing Zaiping provided further explanation. Because people are familiar with myocardial infarction, when severe chest pain occurs, they often think of the possibility of myocardial infarction first, and even the doctor who receives the patient will often be “preconceived” and treat it as a heart attack. However, you can see what we have overlooked through the following 6 aspects? First, patients with myocardial infarction have a history of angina attacks, while patients with aortic coarctation rarely have symptoms of chest pain before the onset of the disease. Secondly, patients with myocardial infarction usually have high blood pressure before the attack, and their blood pressure will decrease at the onset, while patients with aortic coarctation have an increase rather than a decrease in blood pressure at the onset. Thirdly, the chest pain of patients with myocardial infarction is persistent and severe, and it is gradually increasing, but the chest pain of patients with aortic coarctation peaks as soon as it appears. Fourth, the chest pain of patients with myocardial infarction is mainly located in the anterior chest, while the chest pain of patients with aortic coarctation is mainly located in the dorsal chest. Fifth, the chest pain in patients with myocardial infarction is mainly chest tightness, while the chest pain in patients with aortic coarctation is mainly tearing-like pain. Sixth, the electrocardiogram of patients with myocardial infarction has the typical manifestations of myocardial infarction, while the electrocardiogram of patients with aortic coarctation does not have the typical manifestations of heart attack. Chest pain should be noted to correctly determine the cause of the disease and prevent misdiagnosis and omission from occurring. Attention should be paid to keeping warm in spring, and strengthening physical exercise and maintaining good work and rest habits will be beneficial to the prevention of cardiovascular diseases.