In recent years, many patients with recurrent chest tightness, with or without abdominal discomfort, have gone to many hospitals, have gone to many doctors, have done many tests, have spent a lot of money, but still can not find the cause of the disease, the doctor told to go home to recuperate, but the patient is uncomfortable to death. Some treated as stomach problems, some treated as heart disease ….. The causes of the disease are varied. The most typical is a 40-year-old male patient, vomiting dozens of times a day, to the city hospital gastroenterology and ear, nose and throat department to seek expert treatment for more than a year, but still no effect. I analyzed the patient’s situation: the patient had poor sleep quality, irritability, and economic stress, probably suffering from anxiety-induced somatization disorder – neurotic vomiting, which improved significantly after five days of medication, and the symptoms disappeared. Such patients are treated with the general sedative alprazolam in mild cases and with anxiolytics in severe cases. However, the efficacy of each anti-anxiety drug is 50%-70%, and the efficacy varies greatly among individuals, even completely, so it must be treated differently, and the efficacy can be observed only after at least ten days of medication. Individuals need a combination of medications. This type of patient is becoming more and more common in outpatient work. In foreign countries, they are mostly diagnosed and treated by general practitioners, but in China, only a part of them are diagnosed and treated by psychiatrists, while most of them are not clearly diagnosed and even treated as difficult diseases, which bring great pain and loss to patients’ mental and economic well-being.