“Coronary heart disease, acute myocardial infarction.” . Coronary heart disease is one of the major diseases endangering human health, and in China, it has become the third leading cause of death in China (after tumor and cerebrovascular disease). Acute myocardial infarction refers to the ischemic necrosis of the myocardium caused by acute occlusion of the coronary arteries and interruption of blood flow, which can be characterized by persistent retrosternal pain, shock, arrhythmia and heart failure, as well as increased serum cardiac enzymes and electrocardiographic changes. Acute myocardial infarction can also occur as a result of coronary artery spasm without coronary atherosclerosis, or occasionally as a result of coronary embolism, inflammation, or congenital malformation. A few days before the onset of acute myocardial infarction, most patients have prodromal symptoms, frequent chest pain events, abnormal electrocardiograms, and high or significantly inverted T waves, at which time the patient should be alerted to the possibility of myocardial infarction in the near future. The patient had chest tightness and pain after activity, dressing and full meal many times in the week before the onset of the disease, and the chest pain was relieved after resting for a while. Since the pain was not severe, the patient did not take it seriously and neither talked to his family nor went to the hospital until the onset of the disease. Patients need to be reminded to pay special attention to the symptoms of chest pain, which is the most prominent symptom of acute myocardial infarction in coronary heart disease. The pain is the most prominent symptom of acute myocardial infarction in coronary artery disease. The onset of pain is mostly without obvious cause and often occurs in quiet time, with the same location and nature as angina pectoris, but the pain is heavier and lasts for a long time, up to several hours or even several days, and nitroglycerin is ineffective. Patients are often irritable, sweating, fearful or have a sense of near death. A small number of patients may have no pain and may start with shock or acute pulmonary edema. In addition, shock may be present in about 20% of patients, mostly within a few hours to a week after onset of illness. Patients may be pale, irritable, and have cold skin, a weak pulse, a drop in blood pressure of <10.7 Kpa (80 mmHg), or even fainting. If the patient only has a decrease in blood pressure without other manifestations is called hypotensive state. The main reasons for the occurrence of shock are: a sharp decrease in left ventricular efflux due to severe damage to the myocardium (cardiogenic shock); secondly, neuroreflex peripheral vasodilatation caused by severe chest pain; in addition, there are factors of insufficient blood volume due to vomiting, sweating, and insufficient intake. Arrhythmias occur in some patients, and about 75-95% of patients have arrhythmias, mostly within 1-2 weeks of onset, and most often within 24 hours. Ventricular arrhythmias are the most frequent among arrhythmias, such as premature ventricular beats, and sudden death due to ventricular tachycardia or ventricular fibrillation in patients with parts. Atrioventricular block and bundle branch block are also not uncommon, and supraventricular arrhythmias are less common. Bundle branch block is more common in anterior wall myocardial infarction, atrioventricular block in inferior wall myocardial infarction, and supraventricular arrhythmias are more common in atrial infarction. Heart failure is a serious complication of myocardial infarction. After infarction, the contraction of the heart is significantly weakened and uncoordinated, so acute left heart failure is likely to occur in the first few days of the disease, with symptoms such as dyspnea, cough, irritability, and inability to lie down. In severe cases, acute pulmonary edema occurs, and cyanosis and large amounts of pink foamy sputum may be present. Some patients also have systemic symptoms, such as fever, tachycardia, increased white blood cells and increased erythrocyte sedimentation. This is mainly caused by the absorption of tissue necrosis and usually appears within 1-2 days after the infarction, and the temperature is usually around 38℃ and rarely exceeds 39℃, which lasts about a week. Fortunately, only the symptoms of chest pain, not heart failure, shock, arrhythmia and other complications, otherwise, the risk is much greater. The principles of acute myocardial infarction treatment are: protecting and maintaining heart function, improving myocardial blood supply, saving the dying myocardium, reducing the extent of myocardial infarction, and managing complications to prevent sudden death. The most effective treatment for acute myocardial infarction is to open the occluded coronary artery as soon as possible and to carry out effective, adequate and continuous reperfusion therapy. . There are two major types of reperfusion methods: drug thrombolysis and minimally invasive surgical intervention. In the late 1990s, with the development of minimally invasive interventional techniques, emergency percutaneous coronary interventions have increasingly shown their safety and effectiveness. Patients often ask: "Is interventional therapy dangerous?" In fact, the danger of interventional procedures does not lie in the surgical operation itself, but in the patient's cardiac and systemic conditions, including the condition of the coronary artery, the presence of heart failure, and the combination of other serious diseases.