Symptoms of safflower oil allergy are mainly manifested by a certain inflammatory reaction of the skin in the area where safflower oil is applied. This inflammation is mainly manifested by localized erythema, especially flushed spots, and in some cases even a certain amount of inflammatory exudation, as well as the appearance of blisters and even vesicles. This phenomenon is also clinically known as drug contact dermatitis, which is actually a serious adverse skin reaction due to drug allergy, and this reaction is actually a metabolic disease formed due to drug-induced. So when this occurs, the use of safflower oil needs to be stopped promptly. In addition, you need to actively use anti-allergy drugs for treatment, generally if the local obvious exudation, you need to use 3% boric acid solution cold compress, or use saline cold compress, and then take some oral glucocorticoids for anti-inflammatory treatment. For example, you can take oral dexamethasone or prednisone, etc.