If there is an allergic reaction to the skin after applying safflower oil, it is clinically considered as contact dermatitis, and the treatment is as follows: 1. Stop applying safflower oil, if there are scattered erythematous spots with slight itching, you can take oral levocetirizine hydrochloride tablets and choose topical application of glycopyrrolate lotion or compound camphor cream at the same time. 2. If rice-like blisters appear on top of the erythema, you can take compound glycopyrrolate tablets and olopatadine hydrochloride tablets orally, and you can also take moxifloxacin hydrochloride tablets orally. For topical application, topical cold and wet compresses of compound cypress lotion, a mixture of comfrey oil preparation and recombinant human epidermal growth factor gel can be applied topically, and red light treatment can also be combined. During the treatment period, it is necessary to abstain from spicy and stimulating food and alcohol, as well as from squeezing the red spots with hands, while paying attention to rest and reducing late nights.