The patient, male, 78 years old, was admitted to the second ward of the Department of Urology for bilateral hydronephrosis, uremia, and rectal cancer six months after surgery, and was treated with hemodialysis after unsuccessful cystoscopic placement of a double J-tube. Acute myocardial infarction appeared on the second day after hemodialysis, so he was transferred to the cardiology care unit for treatment, and at the same time, hemofiltration was performed with the expectation of improving renal function, but the renal function did not improve after half a month, and the blood creatinine fluctuated from about 700umol/L to 1000umol/L. The patient’s hydronephrosis was not significant, and his chest tightness was aggravated from time to time, so it was decided to perform a left nephrolithotomy. Considering the patient’s new heart attack and application of high-dose anticoagulant drugs, as well as uremia stage and other factors are very likely to cause intraoperative hemorrhage and heart attack aggravation, life-threatening, to the patient’s side to fully communicate, the department after discussion, the next day transferred to the urology department of the second ward of the surgical treatment. The surgery went smoothly, urine output was 5000ml on the first day after the operation, blood creatinine decreased to 400umol/L, creatinine decreased to normal on the third day after the operation, systemic symptoms improved significantly, and the patient was discharged from the hospital. This is the true embodiment of the value of ultrasound-guided percutaneous nephrolithotomy, the entire surgical process is less than ten minutes, an F10 fistula tube, save a life, and no other treatment can be replaced. ultrasound-guided percutaneous nephrolithotomy, perirenal and subperitoneal effusion drainage, renal cysts perforation sclerosis, diagnostic effusions and masses perforation and other technologies, over the past three years, there are dozens of cases of patients treated, the success rate of 100%, none of the cases were treated. The success rate is 100%, and no case was changed to open surgery. On this basis, the department has systematically carried out ultrasound-guided percutaneous nephrolithotripsy, which has cured nearly 200 cases, among which dozens of complicated kidney stones have been crushed in multiple stages and channels with satisfactory results.