The causes of lymphoid follicular hyperplasia at the base of the tongue are tonsillitis, papillitis of the tongue, ulcers of the tongue mucosa and herpes virus infection. 1. Tonsillitis: patients with tonsillitis will have lymphoid follicular hyperplasia at the base of the tongue, as well as enlarged lymph nodes in the neck. 2. Inflammation of the papilla of the tongue: due to the presence of a large number of taste receptors on the papilla of the tongue, when there is inflammation of the papilla of the tongue, it will lead to lymphoid follicular hyperplasia in the root of the tongue. 3. Ulceration of the tongue mucosa: when ulceration of the tongue mucosa occurs at the base of the tongue, there will be hyperplasia of lymphoid follicles at the base of the tongue. 4. Herpes virus infection: When the herpes virus infects the isthmus of the pharynx, it can lead to lymphoid follicular hyperplasia at the base of the tongue. There may be other reasons for lymphoid follicular hyperplasia at the base of the tongue, so it is important to go to the hospital in time for examination to clarify the cause of the disease and then carry out targeted treatment.