What are the culprits of coronary heart disease

As far as current research is concerned, the culprit of coronary heart disease is atherosclerotic plaque, which causes atherosclerosis of the coronary arteries, thus further leading to coronary heart disease. At present, the cause of coronary heart disease has not been fully determined, but the view that a combination of risk factors leads to the formation of atherosclerotic plaques causing coronary heart disease is widely recognized. Common risk factors include age, gender, dyslipidemia, hypertension, smoking, diabetes and glucose intolerance, obesity, and family history. The combination of these risk factors leads to endothelial damage, lipid deposition on the surface of the damaged endothelium to form plaques, accompanied by degeneration and calcification of the middle layer of the arteries, which leads to narrowing of the coronary arteries and ischemia of the myocardium, resulting in coronary heart disease. For patients with coronary heart disease, it is necessary to actively seek medical treatment, scientific treatment under the guidance of the doctor, to slow down the development of the disease and improve the survival period.