The possible reasons for a little pain at the urethral orifice when touched: first, urethral polyps or caruncles, which can appear after combined infection, local pain, pain is obvious when touched, and accompanied by redness, swelling and erosion of the mucosa of the urethra, or with local bleeding, increased secretions, etc. A detailed examination of the urethra and culture of the secretions is needed to confirm the diagnosis. Second, periurethral inflammation can appear as edema around the urethra with redness of the mucosa, pain when touched or stinging sensation when urinating, and a burning sensation at rest. It is necessary to conduct a routine examination of the urethral discharge or a urethral swab to further confirm the diagnosis. Thirdly, if there are acromegaly, distributed around the urethra, it can appear painful when touched. The appearance of the urethra can be seen with papilla-like or cauliflower-like protrusions, accompanied by surface bleeding and increased secretions. It is necessary to perform local excision and then pathological examination to confirm the diagnosis. Anti-viral treatment is required after the diagnosis.