The pain in the fingertips should be examined by a specialist to clarify the diagnosis. In one patient, it is due to nail infection, a common local soft tissue infection, and can be treated with topical ichthyolite ointment in the early stages, along with oral anti-infective drugs, such as penicillin V potassium tablets and rosmarinic acid capsules to relieve the patient’s local discomfort. In addition, some patients with diabetes, especially those with a long history of complications of peripheral vascular disease and peripheral neuritis, can take appropriate B vitamin supplements to nourish the nerves. Severe pain can also be treated with pain relieving drugs such as oral Nimesulide dispersible tablets, as well as active treatment of underlying diseases, monitoring changes in blood glucose, as increased blood glucose can also lead to aggravation of the patient’s symptoms, and paying attention to a reasonable diet.