Appendicitis can present with nausea. In the early stages of appendicitis, gastrointestinal symptoms may occur, such as nausea, vomiting, and even anorexia in some patients, but in clinical practice, the symptoms are usually mild, and some patients may even have diarrhea. If the appendix is located in the pelvic area, it can irritate the rectum and bladder, causing an increase in the number of bowel movements and a feeling of urgency during bowel movements. If the appendix is perforated and causes diffuse peritonitis, it can also lead to paralytic intestinal obstruction, and the patient may experience abdominal distention and decreased defecation. In addition, patients may experience systemic conditions such as malaise, increased heart rate, fever, and in some cases, chills, high fever, and mild jaundice if portal phlebitis is present.