In China, mother-to-child transmission is the most important way to transmit hepatitis B. Immunization of pregnant women with hepatitis B can be done by injecting 200-400 IU of hepatitis B immunoglobulin every month during the 7th, 8th and 9th months of pregnancy to neutralize the hepatitis B virus in the body and block the intrauterine transmission of hepatitis B virus; the newborn baby will be injected with hepatitis B immunoglobulin within 24 hours of birth, and can also be injected at different sites at the same time. The hepatitis B vaccine can also be given at different sites at the same time, followed by monthly vaccination according to the 0-1-6 immunization program, with a blockage rate of 95%.