After drinking alcohol, it is best to give tetanus injection 24 hours later, because alcohol causes redness of the skin, and skin test when injecting tetanus vaccine can easily cause false negatives or false positives, which can easily lead to allergy. If you have been drinking after the trauma, you can do the tetanus vaccine skin test after 24 hours of alcohol metabolism in your body, and then do the tetanus injection according to the results of the skin test. Before the intramuscular tetanus injection can also be a thorough wound debridement, suture, if necessary, can be repeatedly rinsed with iodophor, hydrogen peroxide, to minimize the infection of anaerobic bacteria, clostridium difficile, tetanus bacteria, all help to reduce the chances of tetanus infection.