The difference between frozen shoulder and cancer shoulder pain mainly lies in the causes of the disease, clinical manifestations and corresponding treatment methods. 1. Causes: Cancer shoulder pain is usually caused by cancer cells invading bone tissues, resulting in radiating pain in the shoulder area; whereas frozen shoulder is caused by chronic strain injury and acute trauma. 2. Clinical manifestations: Cancer-induced shoulder pain is usually persistent and severe, and is not alleviated after resting; while the pain of frozen shoulder is usually intermittent and can be relieved after resting. 3. Corresponding treatments: cancer shoulder pain is mainly treated by radiotherapy and chemotherapy; while frozen shoulder is mainly treated by physiotherapy and enhanced functional exercises. If patients have shoulder pain, it is suggested that they should consult the doctor in time to clarify the cause of the disease and standardize the treatment, so as not to threaten their health.