Growth hormone is not effective for any child with short stature. Growth hormone therapy is specifically effective for growth hormone deficiency, or pituitary dwarfism. Research has also proven that it is effective for certain other causes of dwarfism. For example, congenital ovarian hypoplasia syndrome, children born younger than gestational age with persistent dwarfism, and idiopathic dwarfism. The following children with dwarfism do not need to be treated with growth hormone or have not been proven to be effective with growth hormone treatment: (1) Familial dwarfism refers to children whose parents are short and whose children are also short, which is genetically determined. This is due to genetic predisposition. Generally, treatment with growth hormone is not needed, and even if it is, the results are not good. So, how can we make these children grow taller? Parents should try their best to create a good environment for them, pay attention to reasonable nutrition, disease prevention, proper exercise, sufficient sleep, regular life and happy spirit from childhood. Use the above favorable environmental factors to promote growth, so that their growth potential can be brought into full play. As for adolescents with short stature who have entered puberty, because the bones are closed or close to being closed, using growth hormone is even more ineffective, and other drugs or therapies will not be effective. (2) Delayed somatic growth Parents are late in growing at puberty, and their children also have late growth. Their final height is normal by the time they reach adulthood. In order to relieve parents’ worries, they can ask a specialist for examination and consultation and regular height monitoring. If the height deviation is not much, there is no need to treat with growth hormone. (3) Children with special symptoms of dwarfism Unproportional appearance, some with short limbs and some with short trunks, is often due to congenital abnormalities in skeletal development; other children with dwarfism accompanied by deformities in appearance or mental retardation may have congenital autosomal abnormalities, metabolic diseases or various growth retardation syndromes. The effect of growth hormone treatment in these children with specific symptoms of short stature has not been reported with certainty. It is important to consider that any drug has potential side effects, growth hormone is relatively expensive and needs to be injected daily, and the drug needs to be stored in a refrigerator at 4~8℃. Therefore, growth hormone should be applied with caution, and indications must be grasped to prescribe the right drug. If it is applied arbitrarily, even if no side effects appear temporarily, the relationship between economic burden and efficacy should be considered to avoid unnecessary waste and long-term side effects that are not yet certain.