Yellow crust on the soles of the feet if it appears on the soles of the feet bilaterally, and appears at an early age consider palmar-plantar keratosis as a high probability. Palmoplantar keratosis belongs to autosomal dominant inheritance, generally can develop as a child, less severe manifestations of dry skin, serious will appear diffuse yellow plaques, the surface is smooth, similar to the callus caused by friction. There is no specific method of treatment, but the main thing is to reduce the thickening of the stratum corneum, lubricate the skin and prevent painful cracking. You need to pay attention to reducing pressure as well as friction, and you can apply topical 5% salicylic acid or 12% ammonium lactate lotion topically. You can also give 10%-20% urea cream for external use, and in severe cases, you can give 0.1% vitamin A acid cream for evening use, and seal the package with plastic wrap after using the medicine to promote the absorption of the drug.