Three-generation IVF is a way to screen embryos and then do the transfer, the advantages of the corresponding program are mainly to accurately screen high-quality embryos and ensure good chromosome condition; the disadvantages are mainly the high price and a certain degree of harm to the embryos. 1. Advantages: three-generation IVF can directly screen high-quality chromosomal embryos, avoid repeated spontaneous abortions, and avoid the generation of genetic diseases as much as possible. 2. Disadvantages: three-generation IVF involves chromosome screening technology, the price of the corresponding technology is high, the overall economic burden of three-generation IVF will be relatively large; the need to take out some of the cells before transplantation, there is a certain degree of harm to the embryo itself, which may cause developmental abnormalities during the development of the embryo. Three-generation IVF needs to be handled in a regular medical institution, and care must be taken to regulate the physical condition and obtain high-quality egg cells and sperms, so as to maximize the possibility of increasing the success rate.