Migraine is a clinical recurrent headache, aspirin, also known as acetylsalicylic acid, is a long history of antipyretic and analgesic drugs, aspirin currently has a relieving effect on some of the migraine attacks, but for most of the migraine treatment effect is not ideal. 1, migraine acute attack can be considered to give treprostinil analgesics, such as sumatriptan, zolmitriptan, but also can be given ergotamine preparations, such as dihydroergotamine or ergotamine orally, but treprostinil and ergotamine alkaloids, which are strong vasoconstrictor, 2, if the patient has heart disease or severe hypertension, it is recommended to be prohibited. 3, if the headache is more severe, but also with other antipyretic and analgesic drugs, such as ibuprofen, acetaminophen, 4, if the headache is a persistent state, can also be given glucocorticoid hormones, such as prednisone orally, 5, when necessary, can also be combined with sedatives, such as benzodiazepines sedatives to improve sleep, relieve the onset of the headache, and so on.