One evening at the end of June, Ms. Cao suddenly lost consciousness in her left limb while going to the bathroom, and her speech was slurred; more than an hour later, Ms. Cao was taken to the hospital emergency room, where a CT angiogram confirmed that she had suffered a stroke and determined that the cause was a complete blockage of the originally mildly narrowed cerebral artery. The cause was a complete blockage of the brain artery, which was mildly narrowed. According to the treatment procedure, intravenous thrombolytic therapy was the preferred option. However, Ms. Cao had a history of gynecological surgery within a week, and intravenous thrombolysis would increase the risk of bleeding from the surgical incision, which was a contraindication to treatment. The specialists decided to use arterial thrombosis treatment, which is a minimally invasive interventional method to deliver catheters and stents to the blocked blood vessel and remove the thrombus directly. During the operation, the interventional team of the neurology department and stroke center of the hospital delivered the embolization device to the narrowed part of Ms. Cao’s diseased vessel and then performed the embolization treatment, which successfully removed the 3 mm long thrombus. However, post-thrombectomy imaging revealed that a new thrombus had formed again, resulting in occlusion of the vessel and interruption of distal blood flow. The interventional team then performed a second embolization of Ms. Cao’s intracranial lesion, and the new thrombus was successfully removed together with the intravascular plaque. What the specialist did not expect was that the subsequent angiographic review showed that the vessel was occluded again. According to previous surgical experience, if repeated mechanical thrombus removal continues to cause significant vascular damage, the blocked vessel cannot be effectively unblocked and the left limb will be permanently paralyzed. If the ischemia caused further expansion of brain tissue necrosis, Ms. Cao would suffer from severe coma or even death. After a brief discussion, the interventional team decided to use a new treatment method, namely transcatheter intra-arterial injection of a new antiplatelet drug, to achieve the effect of clearing the clot and reopening the vessel. However, this approach carries a higher risk of bleeding. With the family’s consent, the catheter was delivered for the third time to the site of the vascular lesion and the new enhanced antiplatelet drug was slowly injected into the lesion through the catheter. As time passed, the drug gradually penetrated, the clot began to dissolve, and the originally occluded vessel was gradually unblocked. To ensure the efficacy of the treatment, additional injections were administered intravenously to maintain the effect. The repeat imaging showed that the blocked blood vessel was finally completely reopened and the blood supply to the right side of the brain gradually returned to normal. The whole operation lasted for 4 hours. In the early morning of the next day, after the anesthesia had fully awakened, Ms. Cao’s left leg, which could not move, could be lifted.