Every fall and winter, some middle-aged and elderly people with a history of cerebral infarction will go to the hospital and ask for infusion, “dredging blood vessels” to prevent recurrence of stroke, this phenomenon has been going on for many years, no matter in the large, medium and small hospitals are so, the mainstream view of the medical profession is that “infusion to prevent cerebral infarction At present, the mainstream view of the medical profession is that “infusion to prevent cerebral infarction” is undesirable, but in reality, the phenomenon of seasonal infusion is quite prevalent, which makes some primary care doctors feel very confused, this paper intends to make a preliminary analysis of this issue and give suggestions for reference. 1, the reason behind the seasonal infusion The reason why patients with cerebral infarction in the change of season requires infusion “through the blood vessels” to prevent the recurrence of stroke, the reasons can be summarized in the following aspects: (1) prevention and control of awareness of the brain infarction to the patients and their families to bring great pain, so there is an urgent need to prevent and control cerebrovascular disease, with the popularization of medical knowledge and health education and awareness-raising campaigns to prevent and control cerebrovascular disease. With the popularization of medical knowledge and in-depth health education, the concept of prevention of cerebrovascular disease is being accepted by the general population year by year, and people gradually have a better understanding of cerebrovascular disease and realize that cerebral infarction is preventable and curable to a certain extent, which is an important basis for the formation of the phenomenon of seasonal infusion. (2) High incidence in winter and spring seasons Cerebral infarction is a clinical syndrome caused by cerebrovascular occlusion, and its incidence is obviously correlated with the seasons [1], especially in the autumn, winter and winter-spring seasonal changes, cerebrovascular disease shows a high incidence of this phenomenon has distinctive features, which is spontaneously recognized by the general population, and this law has been confirmed by the relevant research institutes, which constitutes another important reason for the infusion of fluids in the changing of the seasons. (3) Rapid onset of infusion For acute cerebral infarction, hospitals often use intravenous infusion for treatment, and the drugs used are usually some antiplatelet agents [2] and traditional Chinese medicine injections [3], and some patients benefit from it, and the patients have gained some experience from previous treatment, that is, the infusion tends to partially alleviate the clinical symptoms and the onset of the effect is rapid, so when carrying out the second level of prevention, the patients mostly take the initiative to choose intravenous infusion. Therefore, in secondary prevention, patients tend to choose intravenous fluids. In addition, primary care doctors in clinical practice, for patients with aura of stroke, the use of intravenous vasodilators or antiplatelet agents can often reduce the clinical symptoms of patients to a certain extent, and from the side of the patients continue to get positive feedback, which makes the primary care doctors are also willing to accept the patient’s request to give the patient infusion treatment in the season of high incidence of cerebrovascular disease, which invariably also plays a role in promoting the phenomenon of seasonal infusion. This inadvertently also plays a role in promoting the phenomenon of seasonal infusion. 2, the mainstream view of the medical profession Due to the “infusion to prevent cerebral infarction” phenomenon is becoming more and more common, which has caused the medical profession to pay attention to the mainstream attitude towards this phenomenon is negative, mainly based on the following reasons: (1) infusion to prevent cerebral infarction has no scientific basis, the patient’s preventive infusion is mainly the use of some of the activation of the blood to remove stasis, reduce blood viscosity, anti-free radicals, and anti-free radicals, as well as the use of the infusion of cerebral vascular diseases. Preventive infusion of patients is mainly used to activate blood stasis, reduce blood viscosity, anti-free radicals and anti-platelet aggregation of drugs, these drugs may theoretically have a certain effect on the prevention and treatment of cerebrovascular disease, but the feasibility of a program needs to be verified by evidence-based medicine. At present, “routine” infusion prevention methods have not been scientifically, rigorously, large-scale clinical verification. (2) Infusion increases the chance of infection and infusion reactions Infusion is a direct intravenous administration, which increases the chance of infection and infusion reactions[4] (e.g., fever, pulmonary edema, phlebitis, air embolism, etc.). During infusion, debris entering the blood vessels can trigger blood infections and cause endothelial damage to the blood vessels, where the damage can lead to lipid deposition, making atherosclerosis, and over time forming new % [‘ C’ z) t5 d6 B7 P7 twww.jcys120.cn的栓塞. (3) infusion is not suitable as a secondary preventive measures secondary prevention of cerebrovascular disease requires long-term and even lifelong medication, infusion is only a temporary way of drug delivery, and thus is not suitable as a secondary preventive measures. 3, seasonal infusion phenomenon of enlightenment then infusion can really prevent cerebral infarction recurrence? What are the misunderstandings in the application of infusion? How to correctly treat the recurrence of cerebral infarction? As a way of intravenous drug delivery, infusion provides a fast way for clinical use when the condition changes rapidly, and plays an important role in the prevention and treatment of acute cerebrovascular disease, but there are also misunderstandings in the application of infusion, which are mainly due to inappropriate selection of the indications for infusion. It should be emphasized that although cerebral infarction is characterized by high incidence in winter and spring, the season should not be used as the basis for choosing the way of medication, and the decision of whether or not to treat with infusion should be made according to the severity of the disease. (1) Cerebral ischemic symptoms Transient ischemic attack (TIA) and posterior circulation ischemia are common clinical aura of cerebral infarction. At this time, cerebral ischemic symptoms are the warning sign of acute cerebral infarction, which should be regarded as an emergency for urgent treatment, and then intravenous drug administration should be used to control the condition as soon as possible. The pathogenesis of both mainly involves microembolism, cerebral vasospasm and hemodynamics (hypoperfusion) [5], which can be treated with targeted selection of antiplatelet aggregation drugs such as ozagrel sodium, vasospasm-relieving drugs such as guipizide maleate or nimodipine, and volume-expanding drugs such as low molecule dextrose, etc. TCM injections such as haematoxylin, dengzhanshenxiaoxin, etc., which invigorate blood circulation to eliminate blood stasis, or shengmai injection, etc., can be identified as a treatment method. To benefit qi and nourish yin. After the symptoms improve and the condition stabilizes, the risk factors of the patients can be evaluated and oral drug treatment can be adopted. (2) No cerebral ischemic symptoms A history of cerebral infarction is an independent risk factor for cerebrovascular disease, and patients without cerebral ischemic symptoms must also be actively engaged in secondary prevention, the main purpose of which is to reduce the causes of atherosclerosis, prevent rupture of sclerotic plaques, stabilize the inner lining of the arteries, and control the development of atherosclerotic plaques [6]. At this stage, the patient’s condition is relatively stable, and in addition to instructing patients to change their poor lifestyle, oral medications can be used to control risk factors, mainly for the treatment of underlying diseases, including hypertension, diabetes mellitus, hyperlipidemia, hyperhomocysteinemia, atrial fibrillation, and atherosclerotic stenosis of the arteries supplying blood to the brain. Currently, the measures with evidence-based medical evidence are mainly oral aspirin and statin drugs, but also can be used to activate blood circulation and eliminate blood stasis traditional Chinese medicine, such as Panax ginseng, Ginkgo biloba, etc., to improve vascular function and promote the establishment of collateral circulation. (3) Pay attention to seasonal factors The onset of cerebrovascular disease has obvious seasonal characteristics, which is related to the seasonal changes in vascular diastolic function, especially during the change of seasons in autumn, winter, winter and spring, when the climate is changing, the alternation of heat and cold often leads to vascular diastolic dysfunction, and the cold tends to make the blood vessels constrict, and vasospasm occurs on the basis of atherosclerosis, which leads to cardio-cerebral and cerebral vascular events, so patients with a history of strokes in the change of seasons should be instructed to closely observe the change of conditions. Therefore, during the change of season, patients with a history of stroke should be instructed to closely observe the changes in their condition, and once symptoms such as headache, dizziness, numbness and weakness of the face and limbs appear, they should “immediately” go to the neurology department for consultation. When it is clearly diagnosed as a transient ischemic attack or posterior circulation ischemia, the patient can be treated by infusion of fluids in order to control the condition in time, and since there is no treatment for cerebral infarction with better effects than prevention, it is important to prevent cerebral infarction. Since no treatment for cerebral infarction is more effective than prevention, prevention is the most effective measure to reduce the incidence of cerebral infarction. In conclusion, correct understanding of the etiology and pathogenesis of cerebral infarction and long-term intervention of risk factors of cerebrovascular disease are crucial for the prevention of recurrence of stroke, and such prevention should pay attention to stratified management and adopt different treatment methods for patients with different conditions. For those who are stable, oral medications; for those who are unstable, intravenous fluids. Since the onset of cerebral infarction is obviously seasonal, the condition should be closely observed during the change of seasons, and the decision of whether or not to use infusion therapy should be made according to the needs of the condition.