Cerebrovascular disease is the main killer of human health, cerebral infarction is ischemic stroke, accounting for the first of cerebrovascular disease, accounting for about 85% of all strokes, disability rate and death rate is very high. Our country is ahead of other countries in the treatment of cerebral infarction by ozone autologous therapy Combining ozone technology with traditional atherosclerotic occlusion treatment technology can effectively reduce the pain of atherosclerotic occlusion patients and shorten the treatment cycle, which is a major breakthrough in the treatment of atherosclerotic occlusion. Ozone macroautohemotherapy is to take 100~200ml of anticoagulated whole blood from the patient’s peripheral vein and mix it with equal volume of certain concentration of medical ozone (ozone, medical oxygen mixture, apply bacterial filter when taking gas) under normal pressure, and then the autologous blood after ozone action is infused back under normal pressure (risk of air embolism when infusing back under high pressure). Its therapeutic mechanism is to activate red blood cell metabolism, promote oxygen release to improve microcirculation O3 is a strong oxidant, can activate red blood cells, promote the release of oxygen from red blood cells, increase the amount of oxygen-carrying blood and tissue oxygen supply. O3 can increase the deformation ability of erythrocyte, reduce the agglutination of platelet and viscosity of erythrocyte, so that erythrocyte can pass through the microcirculation, O3 can increase the activity of superoxide dismutase in blood, promote the decomposition of oxygen radicals, which is beneficial to the treatment of ischemia-reperfusion injury. o3 can activate immune cells, so that the release of cytokines, such as interferon, interleukin, tumor necrosis factor, etc., increases, and improve the body’s immune system. O3 can activate immune active cells, make interferon, interleukin, tumor necrosis factor and other cytokines release increase, improve the immunity of the body. Cerebral infarction and other vascular diseases patients are mostly accompanied by dyslipidemia, ozone therapy can promote the decomposition of fat, both to assist in the treatment of cerebral infarction and to prevent the occurrence of cerebral infarction. Ozone can accelerate the trihydroxy acid cycle, promote the metabolism of carbohydrates and fats, and decompose the fats adhering to the walls of blood vessels.