Wake up with coffee-colored saliva may be related to oral diseases, digestive diseases, need to be specifically analyzed. 1. Oral diseases: such as dental caries, periodontitis, gingivitis, mucous membrane damage such as ulcers or erosion, or pharyngeal congestion and edema, can lead to coffee-colored drool in the morning, often accompanied by pain, increased salivary secretion and other symptoms. 2. Gastrointestinal diseases: such as esophageal ulcers, gastric ulcers, gastritis, etc., there is gastrointestinal bleeding phenomenon, blood reflux to the oral cavity will appear coffee saliva, but also often nausea, vomiting, abdominal pain, acid reflux and so on. If often appear in the morning with coffee-colored saliva should promptly seek medical attention to clarify the cause of the disease, active treatment, so as not to delay the condition.