Lumbar puncture is one of the important neurological operations used to diagnose diseases, because of the connection with the cranium and brain, the following matters need to be noted after lumbar puncture: first, lumbar puncture is a surgical operation, the wound must be kept dry, and keep the puncture site of the operation without contact with water, and pay attention to postoperative medication change. Secondly, one must lie flat on the bed for 6 hours to achieve the production of cerebrospinal fluid equal to or more than the amount of cerebrospinal fluid released, to avoid the premature lifting of the head to appear the intracranial pressure decrease leading to low cranial pressure headache or cerebral hernia formation. Third, after the operation, pay attention to light diet, eat easily digestible food, avoid eating spicy food. Fourth, after the operation, you need to keep the mood of peace, avoid tension, keep the mood of relaxation, conducive to the early recovery of the body. Fifth, if there is any discomfort such as headache or dyspnea, you must call the doctor in time, according to the situation of rehydration or symptomatic treatment.