Vocal fold hypertrophy may be caused by improper use of voice, air pollution, excessive smoking and drinking, acute laryngitis, chronic inflammation of the respiratory tract, and systemic diseases. 1. Improper use of the voice: often shouting, talking too much, resulting in damage to the vocal folds, congestion, hypertrophy. 2. Air pollution: often in the dust, all kinds of harmful gases, air burning and dry, less humidity in the environment, resulting in vocal folds mucosal tissue damage, causing vocal folds hypertrophy. 3. Excessive smoking and drinking: Nicotine and carbon monoxide in tobacco can cause spasm of the blood vessels in the vocal folds, resulting in hypertrophy of the vocal folds. Alcohol contains ethanol can promote the expansion of the vocal cord blood vessels, congestion, causing vocal cord mucosal damage, hypertrophy. 4. Acute laryngitis: repeated episodes of acute inflammation of the mucosa of the vocal folds, resulting in hyperplasia and hypertrophy of the mucosa of the vocal folds. 5. Chronic inflammation of the respiratory tract: purulent inflammation of the nasal cavity, sinuses, nasopharynx, etc., which can spread to the vocal folds and cause hypertrophy of the vocal fold mucosa. 6. Systemic diseases: such as diabetes, endocrine dysfunction, heart disease, etc., resulting in vasoconstriction disorders of the laryngeal vocal folds, leading to vocal fold hypertrophy. Vocal fold hypertrophy, it is recommended to consult a doctor to identify the cause of the disease and follow the doctor’s instructions for treatment.