Heart discomfort with minoxidil may be caused by the side effects of the drug, may also be the original heart disease condition aggravation, by analyzing the causes of heart discomfort after the use of drugs, generally from stopping the use of minoxidil, the use of therapeutic cardiac drugs and other aspects of the beginning of the treatment. 1. Side effects of the drug: Minoxidil cardiovascular system side effects, such as chest pain, blood pressure changes, palpitations and pulse rate changes, etc., it is recommended to immediately stop the use of Minoxidil, symptomatic treatment, all need to be carried out under the guidance of a physician. 2. Aggravation of heart disease: patients with underlying heart disease may experience aggravation of their existing cardiovascular disease with the use of Minoxidil. The discomfort can be relieved by oral heart disease drugs, such as metoprolol tartrate. Note that Minoxidil can cause mild erythema, itching, non-specific allergic reactions and other adverse reactions, and is contraindicated in patients who are allergic to Minoxidil. With minoxidil heart discomfort, we should promptly go to the hospital, clear causes, targeted treatment, to avoid further development of the disease.