Children with fever, headache and other manifestations, may be due to acute infection of the upper respiratory tract, pneumonia, purulent meningitis and other causes, can be targeted to the use of drugs to treat the primary disease and symptomatic treatment. 1. Upper respiratory tract infection: common upper respiratory tract infectious diseases include colds, acute bronchitis and other diseases. Etiological treatment needs to be based on the infectious agent, such as viral infections usually no specific drugs, can be nebulized sputum and other treatments, chlamydial infections can be used azithromycin and other macrolides, for bacterial infections can be used for antibiotics such as cefixime. 2. Pneumonia, purulent meningitis and other diseases of the treatment strategy is similar to the upper respiratory tract infection, but antibiotics need to choose easy to reach the site of infection, sensitive antibiotics, such as purulent meningitis is often used meropenem anti-infective, the course of treatment needs to be appropriately prolonged. Symptomatic supportive treatment: Low fever usually does not require pharmacological intervention, and can be cooled by increasing water intake and warm water baths. High fever can be cooled with medications such as acetaminophen and ibuprofen as prescribed. Both of these medications also have some analgesic effect on mild headaches. Rest and a balanced diet are usually recommended. The above medications should be used under the supervision of a clinician; children with fever and headache are advised to go to the hospital and follow the doctor’s instructions for treatment.