The exact time for a patient with gastric cancer to progress from intermediate to advanced stage is closely related to the patient’s pathological type and physical quality, etc. Generally speaking, from clinical experience, about 3-6 months pass for the development of middle stage gastric cancer to advanced stage. If radiotherapy, chemotherapy or even surgery is carried out during this period, it is possible to extend the time appropriately by about 1-2 years. Therefore, once detected, neoadjuvant chemotherapy should be administered to reduce the pathological stage to the early stage, so that patients can be effectively treated with surgery, and after surgery, radiotherapy, chemotherapy and targeted therapy should be appropriately selected according to the pathological type, which can help to extend and improve the survival of gastric cancer patients.