If patients have palpitations and wake up at night in bed, there are usually several factors as follows: 1. Factors of endocrine system diseases, the most common diseases are hyperthyroidism and hyperadrenocorticism, patients will have palpitations. 2. Endocrine factors, if there is a previous history of diabetes mellitus, the patient is prone to hypoglycemic reaction during sleep, the patient will have palpitations, accompanied by cold sweat, and also wake up in sleep. 3 If the patient has coronary atherosclerotic heart disease, especially in the case of arrhythmia, the patient will have palpitations and palpitations at night. 4. If there is an infection of varying degrees, resulting in an increase in body temperature, palpitations will also occur at night. 5. Plant nerve dysfunction