Tetanus is a critical illness, the mortality rate is relatively high, and treatment is quite difficult. Specific treatment includes the following: 1, for the wound that triggers tetanus to do a thorough debridement, if necessary, you can do drainage, do not let the wound remains sinus tract or dead cavity and other hypoxic environment, reduce or block the production of tetanus bacillus toxin. 2, treatment can be used tetanus antitoxin to neutralize the toxin produced by the tetanus bacillus, you can also use tetanus immunoglobulin to treat, before using the drug need to do allergy testing. 3, for tetanus patients in the hospital, isolation measures should be taken to avoid light, sound and other stimuli, so as not to induce spasms, if there are spasms, you can choose some sedatives to relieve, if spasms are persistent, you can continue intravenous drip sedation, if there is laryngospasm or laryngeal edema affect breathing, the need to do timely tracheal intubation serious tracheotomy and on the ventilator, in addition should pay attention to the body temperature In addition, we should pay attention to the change of body temperature, once there is a fever, you can first take physical cooling, and then use drugs if necessary. 4, in the course of treatment should also prevent complications, such as pneumonia, pulmonary atelectasis, if there is urinary retention should also be intubated catheterization, etc., can choose some antibiotics to fight the residual tetanus bacillus in the body. At the same time, it is necessary to pay attention to the patient’s nutrition, if necessary, nasal feeding to replenish energy, monitoring blood electrolytes, pay attention to the balance of water and electrolytes. Tetanus is a critical illness that can be life-threatening, so tetanus is important for prevention, if there is trauma, should be timely inoculation tetanus antitoxin or tetanus immunoglobulin, once the onset, should go to a hospital in good condition for treatment, do not delay.