Cephalosporins and Roxithromycin are two different kinds of antibacterial drugs, each with its own advantages and disadvantages, and you can’t simply say which one is more effective. 1. Cephalosporins: broad-spectrum antibiotics, with good antibacterial effects on Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Influenza bacillus, and Streptococcus pyogenes. Cephalosporins adverse reactions include allergy, gastrointestinal irritation, kidney damage and so on; it is forbidden for those who are allergic to cephalosporins. It is forbidden to drink alcoholic beverages during the medication. 2. Roxithromycin: it belongs to the macrolide class of antibacterial drugs, and has a good antibacterial effect on Streptococcus pyogenes, Mycoplasma pneumoniae, Chlamydia, and sensitive bacteria. Adverse effects of roxithromycin include skin redness, itching, gastrointestinal reactions, impaired liver and kidney function. It is contraindicated for those who are allergic to Roxithromycin, other macrolides and their contained ingredients. You should choose the right medication according to your specific condition and under the guidance of a professional doctor, and never take medication on your own to avoid aggravating your condition or damaging your health.