Shoulder pain from sleeping can be caused by the following reasons: First, frozen shoulder, when frozen shoulder is serious, the shoulder can be pressurized while sleeping, causing obvious pain in the shoulder, which should be diagnosed early by checking the body and taking x-ray and MRI of the shoulder joint. Second, myofasciitis, myofasciitis can often radiate to the ipsilateral shoulder and upper limbs, resulting in soreness, pain, and weakness, especially at night when the shoulder is under pressure, and the pain is very obvious. Third, cervical spine disease, when cervical spondylosis compresses the nerve roots, shoulder pain can occur, especially at night when the sleeping posture is incorrect or when the neck is bent shoulder pain is particularly obvious, then early cervical spine X-ray, MRI examination, to early diagnosis and treatment.