Genital blisters can be considered to be caused by genital herpes, contact dermatitis or drug rash. 1. Genital herpes: a chronic recurrent disease that occurs when the herpes simplex virus infects the skin and mucous membranes of the genitourinary tract and perianal area, mostly in sexually active men and women, and can be seen on the penis, glans, labia majora and minora, mons veneris and other parts of the penis, the skin lesions at the onset of the blisters scattered or clusters of blisters, which can be broken down into vesicles or shallow ulcers. 2. Contact dermatitis: lesions are mostly confined to the contact area, such as contact dermatitis caused by underwear dyes can occur in the genital area, with papules or mounds of herpes, causing blisters or blisters in severe cases. 3. drug rash: also known as drug dermatitis, such as the occurrence of fixed drug rash, good in the genital skin – mucous membrane junction, lesions can be limited to the clear boundary of the patch or patch, serious cases will have erythema based blisters, blisters, mucous membrane folds are easy to vesiculation oozing. When the genital blisters, it is recommended to consult a doctor in a timely manner, to clarify the cause of the disease and then treat it, and to prevent unclean sex.