There is no absolute fast-acting medication for the treatment of headache and nausea. If it is caused by lack of sleep, nervousness and other physiological factors, generally do not need to take drugs. If it is caused by migraine, cervical spondylosis and other diseases, you need to take oral non-steroidal anti-inflammatory drugs, muscle relaxants, such as ibuprofen, chlorzoxazone and so on. 1. Physiological factors: If long-term sleep deprivation, nervous tension, excessive stress, smoking and alcohol abuse, etc., may lead to transient headache and nausea, which is a normal physiological phenomenon, generally do not need to take drugs. After appropriate rest, smoking and alcohol can be relieved. 2. Migraine: headache and nausea may also be caused by migraine, patients need to take oral non-steroidal anti-inflammatory drugs under the guidance of a doctor, such as ibuprofen, diclofenac sodium, naproxen, aspirin, etc., the majority of patients can alleviate the symptoms of headache and improve the prognosis. 3. Cervical spondylosis: headache and nausea are also considered to be caused by sympathetic cervical spondylosis, patients can follow the doctor’s instructions to take oral non-steroidal anti-inflammatory drugs, such as celecoxib, etoricoxib, etc.; or follow the doctor’s instructions to take oral muscarinic, such as clozosazone, etoperidolone, etc.. There are many causes of headache and nausea, we suggest that patients identify the causes of the disease in a timely manner, and actively cooperate with the doctor to take relevant therapeutic measures. Do not blindly use drugs on your own, so as not to cause adverse reactions.