We all know the importance of the skull, which protects our brain from external aggression and ensures that life activities within the skull and brain function properly. In the event of a skull defect, repair surgery is usually required. Does it matter if cranial repair surgery is delayed? It is important to choose the right time for cranial bone repair surgery, not too early or too late, according to the actual situation of the patient, symptomatic treatment, so as to ensure that a better surgical effect can be achieved. Regarding the timing of cranial bone repair surgery, the advice given by experts is: for those patients with open comminuted skull fracture with good wound cleanliness or without cranial hypertension, cranial bone repair surgery can be done at that time, and the recovery will be better at this time; while those patients with closed craniocerebral injury due to intracranial hypertension to bone flap, they have to pay attention to about three months after the surgery before cranial bone repair surgery. In addition to knowing the right time for cranial repair surgery, you also have to be aware of some of the contraindications to cranial repair surgery. There are three contraindications to cranial repair surgery: 1) patients with severe craniocerebral injuries who have not yet recovered cannot have surgery; 2) patients with epilepsy, whose recurrent seizures are not effectively controlled, cannot have surgery; and 3) patients with localized infections and poor soft-tissue conditions cannot undergo this surgery. In order to get a better result of cranial repair surgery, you have to know the right time, pay attention to some contraindications, and more importantly, you have to choose a good repair material. At present, many hospitals use general titanium alloy for the repair surgery, but this material will make the patient become more sensitive to hot and cold reactions after the surgery, and chronic headaches may also occur, so it is recommended to choose a more suitable and safer material. Now some hospitals have successfully adopted the new PEEK material, which is a very safe and advanced material with excellent performance, comparable to autologous skull. Moreover, this kind of PEEK material can be shaped in three dimensions according to the different conditions of each patient, which is worth choosing because of its higher precision and more perfect effect.