I. Living donations between non-relatives are strictly prohibited!
II. The living organ donor and the recipient are limited to the following kinship relationships.
1.Between parents and children
2.Between siblings
3. Spouse: Only those who have been married for more than 3 years or have children after marriage
C. The following cases are not suitable for kidney donation
1, cousins, cousins between the donor will not be considered.
2. Donors under 18 years old or over 60 years old will not be considered!
3, from the ethical point of view, young unmarried women or married women without children or children under the age of 3 should not be considered as donors.
4. Pre-operative examination does not meet medical standards
Organ transplant donors must submit the following materials.
1, organ transplant donors and their parents and adult children who have full civil capacity to jointly sign the written application for voluntary, free organ donation.
2. Proof of the relationship between the living organ donor and the recipient issued by the public security authorities in the household registration area, as well as the original second-generation ID cards and hukou books of both parties.
3, the household registration certificate issued by the public security authorities in the household registration area can reflect the relationship between the living organ donor and the recipient’s relatives.
4. If the living organ donor and the recipient are spouses, the original marriage certificate or proof of having children should be submitted.
The advantages of living kidney transplantation for relatives are as follows.
1. The recipient does not have to wait for a long time for a kidney source, reducing medical costs during the waiting period; the doctor has sufficient time to complete the preoperative examination before surgery, and can schedule the surgery according to the recipient’s physical condition, maximizing the perioperative tolerance and thus improving the transplantation success rate.
2. Donor kidney can be selected according to the ideal tissue matching result. Due to the law of genetics, it is much easier to select a donor with good HLA among relatives than among the general population. Selecting a donor kidney from a relative with good tissue matching can significantly reduce the incidence of postoperative rejection. The suitability of the tissue match is one of the factors affecting the long-term survival of the transplanted kidney.
3. Small trauma in the removal of living relative donor kidney, extremely short thermal ischemia time and cold ischemia time, minimizes the ischemic preservation damage of the donor kidney. The quality of the donor kidney directly affects the transplantation effect. With good quality of the donor kidney, the time period for normalization of kidney function in the early postoperative period, less surgical complications and shorter hospitalization time can be achieved.
4. Because of better blood relationship matching, the postoperative immunosuppressant dosage is smaller than that of cadaveric kidney transplantation, the toxic effect on the transplanted kidney and other organs is small, and the incidence of infection is low, which is conducive to improving the long-term survival rate of the transplanted kidney.
5. The total cost is low because of the short waiting time for transplantation, short hospital stay and low dosage of postoperative anti-rejection drugs.
6. Since the donor kidney is provided by relatives, the recipient and his family cherish and take care of it, pay more attention to the cooperation with doctors, and consciously strengthen the regular postoperative review and adjust the medication under the guidance of doctors, which is conducive to improving the long-term survival rate.
In conclusion, various domestic and international data prove that the immediate and long-term results of kidney transplantation from relatives are significantly better than those of cadaveric kidney transplantation.