Stage III Nephropathy, generally refers to the third stage of chronic kidney disease, the glomerular filtration rate is 30~59ml/(min*1.73m²), which has an impact on the patient’s life span. At this time, a variety of complications may be combined, such as anemia, calcium and phosphorus disorders, hypertension, and so on, if there is no active and effective treatment. In the third stage of nephropathy, glomerular filtration rate decreases, leading to accumulation of metabolites in the body, disturbance of water, electrolyte and acid-base balance as well as damage to various organs in the whole body, and the further development of cardiovascular and cerebral vascular complications, such as uremic cardiomyopathy, heart failure, pulmonary edema and so on, among which cardiovascular and cerebral vascular complications are the main causes of their deaths. The third stage of kidney disease belongs to the early and middle stage of chronic renal failure. Timely treatment for mild and moderate chronic kidney disease, slowing down the progress of chronic kidney disease and preventing the occurrence of uremia is the main therapeutic goal, which can slow down the progress of the disease, reduce the occurrence of complications, and prolong the life span through active treatment. Patients with kidney disease should pay attention to their own disease, actively consult and treat in regular hospitals, follow the doctor’s instructions for medication and regular review.