The number of years that can be survived by chemotherapy for invasive ductal carcinoma grade III is usually related to the stage of the disease, the patient’s physical status, the effect of treatment, etc., which cannot be generalized, and the general five-year survival rate is around 50%~80%. Invasive ductal carcinoma grade III generally refers to breast invasive ductal carcinoma grade III, which belongs to the highest graded type of breast invasive ductal carcinoma, and the five-year survival rate is 50%~80%. Breast invasive ductal carcinoma grade III represents that the cancer cells are less differentiated and more malignant, and at this time, the cancer cells are prone to metastasis, spreading and recurrence. In addition, grade III may occur in both early-stage invasive ductal carcinoma of the breast and advanced-stage invasive ductal carcinoma of the breast. For early-stage invasive ductal carcinoma of the breast, if the pathological report shows that the cancer cells are in grade III, it belongs to the grade with high recurrence risk, and usually chemotherapy, endocrine or targeted therapy is given in combination with the patient’s condition postoperatively, which can relatively alleviate the progression of the disease and prolong the survival period. For advanced invasive ductal carcinoma, the survival period will be shortened even after active treatment. There is no accurate and fixed range of survival time for grade III invasive ductal carcinoma, and it is suggested that patients should actively cooperate with doctors for treatment to avoid aggravation of the condition.