It takes about 1-2 months to achieve effective control of hyperthyroidism with initial medication. Hyperthyroidism is caused by excessive synthesis and secretion of thyroid hormones by the thyroid gland. Treatment for hyperthyroidism includes oral antithyroid medication, surgery and iodine-131 therapy. Oral antithyroid medication is slow to take effect, with a duration of treatment of about 2 years and a 50% relapse rate. Normally, thyroid hormones are secreted by thyroid follicular cells and stored in the follicular lumen. The mechanism of action of antithyroid hormone drugs is to inhibit thyroid hormone synthesis and cannot work on hormones that have already been synthesized and stored. Therefore, in the initial stage of hyperthyroidism, the already synthesized and stored thyroid hormones in the thyroid gland need to be consumed. The stored hormones in the thyroid gland last about 1-2 months, so 1-2 months of medication at the beginning of hyperthyroidism can probably control the symptoms of hyperthyroidism and make the nail function basically normal.