Thick endometrium generally refers to endometrial hyperplasia, which is usually shed after 7 to 10 days of using progesterone, but the treatment cycle is at least three months. If the endometrial hyperplasia is not accompanied by atypical people, you can use progesterone treatment, progesterone is a kind of progesterone, taking progesterone can replenish the body’s progesterone, which will make the endometrium fall off, usually after 7~10 days of medication will fall off, but this treatment should be in accordance with the course of treatment some patients need three months, and some even need six months. Taking progesterone may cause some adverse reactions, such as weight gain or loss, cervical squamous-column junction changes, cervical secretion changes in character, dizziness, headache, tiredness, etc. Allergy to progesterone can not be used, and unexplained bleeding from the vagina, can not be used. Endometrial thickness should be based on the type of endometrial hyperplasia, choose the appropriate drug treatment, to strictly follow the doctor’s instructions for a full course of medication, in order to avoid the wrong treatment or adverse reactions. In addition, the specific use of progesterone need to be under the guidance of a doctor, do not take on your own.