The manifestation of lymphoma is relatively insidious and not easy to be detected. The cure rate will be greatly improved if the symptoms can be detected early and the patient can be seen in time. Some early signs deserve special attention: (a) Progressive lymph node enlargement without a clear cause, especially in the neck, axilla or groin, etc. It is often painless and in bunches. (ii) Unexplained prolonged low-grade fever or periodic fever should also be considered as a possibility of malignant lymphoma, especially with itchy skin, excessive sweating, wasting, and the finding of superficial lymph node enlargement. (C) Lymph node enlargement and fever sometimes improve with anti-infection treatment, but there are often recurrences and the overall trend is progressive. (d) “Lymph node tuberculosis” after regular course of anti-tuberculosis treatment, “chronic lymph node inflammation” after general anti-inflammatory treatment is not effective. If these abnormalities appear in the body, do not take the initiative, but go to the regular hospital for examination in time to avoid delaying the disease.