Elderly foot rot a hole does not heal, may be diabetic foot, vasculitis or tinea pedis caused by the need to take different medications, such as alpha-lipoic acid, warfarin and so on. 1. Diabetic foot: due to peripheral vascular lesions caused by diabetes, it is necessary to take α-lipoic acid, lipid microsphere prostaglandin E1, methyl vitamin B12 and other drugs to take targeted control and treatment of diabetes and peripheral vascular lesions. 2. Vasculitis: anti-platelet aggregation drugs such as aspirin, anticoagulant drugs such as warfarin, thrombolytic drugs such as urokinase, vasodilator drugs such as nicardipine. 3. Tinea pedis: general external imidazole drugs such as miconazole, ketoconazole, external 3% boric acid solution. The choice of specific drugs, need to be based on medical advice.