The whitening of the scrotal skin on both sides may be caused by vitiligo, eczema, florid chaff rash and other reasons. 1. Vitiligo: it is a common acquired pigment loss skin and mucous membrane disease, clinically manifested as white spots, can involve the scrotum skin, resulting in scrotum skin white on both sides. 2. eczema: is caused by a variety of internal and external factors of the superficial dermis and epidermal inflammation, can lead to skin inflammation after hypopigmentation, there will be white spots and other symptoms, scrotum skin white on both sides may be eczema. 3. florid chaff rash: florid chaff rash was previously known as lichen planus, is a superficial infection caused by malassezia invasion of the skin stratum corneum. The lesions are initially pore-centered, well-defined dotted patches that can be brown, light brown, reddish, yellowish or white. It can also lead to whitening of the scrotal skin on both sides. The whitening of the scrotal skin on both sides can also be caused by other reasons, if the symptoms of the whitening of the scrotal skin on both sides, you need to seek medical treatment in time.