The treatment of acute or chronic renal insufficiency caused by nephritis includes allopathic treatment, integrated management of CKD and replacement therapy. Different principles should be applied to acute and chronic renal insufficiency, with the former aiming to save patients’ lives and restore renal function, and the latter aiming to slow down the progression of kidney disease and control complications. 1. Causal treatment: i.e. treatment of nephritis, including reduction of urinary protein and control of blood pressure, hormone and/or immunosuppressant therapy, symptomatic supportive therapy, etc. 2. Integrated management of CKD: including antihypertensive therapy, proteinuria reduction therapy, correction of water, electrolyte and acid-base balance imbalance, correction of anemia and secondary hyperparathyroidism, lipid reduction, uric acid reduction, control of dietary protein, correction of malnutrition and so on. 3. Replacement therapy: patients with end-stage renal disease should choose reasonable renal replacement therapy in due time, including hemodialysis, peritoneal dialysis and renal transplantation. For renal insufficiency caused by nephritis, we should go to the hospital in time and standardize the diagnosis and treatment under the guidance of professional doctors.