Herpes simplex is caused by herpes simplex virus (HSV), clinically characterized by clustered blisters, self-limiting, but prone to recurrence, and is one of the most widespread infectious diseases worldwide. It is one of the most widespread infections in the world. The treatment mainly adopts drug therapy, including topical drug therapy and systemic drug therapy. 1. Topical drug therapy: focusing on convergence of herpes, prevention of secondary infection and antiviral, such as methyl violet solution, penciclovir ointment and sodium phosphonate ointment. 2. Systemic medication: Oral antiviral drugs such as aciclovir, valaciclovir and famciclovir can be taken as prescribed by the doctor, and for patients with obvious complications and immunocompromised patients with severe infections, intravenous drip medication is needed. Herpes simplex patients need to go to the hospital as soon as possible, by the doctor according to the specific conditions, to develop individualized diagnosis and treatment plan, so as not to delay the condition.